La Defense Moves 2026 EN

CHEMICALS PHARMA BOOSTS ITS MOVE-IN VOLUMES CHEMICALS & PHARMA BOOSTS ITS MOVE-IN VOLUMES

The relevant moves come largely from Péri-Défense (Arkema, UCB Pharma, Eisai Laboratories, SGD Pharma…), but also from the Outer Suburbs (Sanofi, Solabia) and even Paris CBD (Takeda, Mylan). Just one move-out is recorded: AstraZeneca, moving to a new building of the "Arboretum" programme in Nanterre, in Péri- Défense.

Chemicals-pharma companies now account for 10% of office space leased at La Défense over the past 5 years, compared to only 4% between 2015 and 2019: a step-up that places the sector among the leading drivers of the period. While the number of moves in, around a dozen, is similar across the two periods, the volume, a 73,000 sq m, has more than doubled since 2021.

ORIGIN OF CHEMICALS-PHARMA COMPANIES ESTABLISHED IN LA DÉFENSE OVER THE 2021-2025PERIOD

9%

Péri-Défense

9%

Paris CBD

9%

Southern Loop Western Crescent - Other Northern Inner Suburbs Southern Outer Suburbs

46%

9%

18%

TOP OFFICE TRANSACTIONS IN THE SECTOR BY SIZE

YEAR OF

VOLUME

BUILDING

COMPANY

ORIGIN

10% share of space leased by chemicals and pharmaceutical companies between 2021-2025

TRANSACTION

SQ M

+600 pts vs 2015-2019

Southern Outer Suburbs

SANOFI

2024

CB3

31,464

ARKEMA

2022

LIGHTWELL

25,094

Péri Défense

GILEAD

2024

LEGENDE

3,023

Southern Loop

Western Crescent - Other

ALBEA

2025

CŒUR DÉFENSE

2,278

MYLAN

2021

TRINITY

2,080

Paris CBD

TAKEDA

2025

CB21

1,469

Paris CBD

Source: Cushman & & Wakefield Mid-market (1,000–5,000 sq m) and Large-market (over 5,000 sq m) deals

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CUS H MAN & WAK EFI ELD

LA DEFENSE MOVES 2026

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